Photo: Alika Jenner / Getty Images Sport / Getty Images
The Minnesota Timberwolves square off against the Portland Trail Blazers as 4.5-point favorites in the first game of the 2025-26 NBA season for both teams on Wednesday, October 22, 2025 at 10 p.m. ET on KUNP and FDSN.
Watch the NBA, other live sports and more on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Use our link to sign up.
Listen to the game on Rip City Radio 620 Portland
Timberwolves vs. Trail Blazers Predictions for Wednesday
Our computer projections model for this contest expects a final score of Timberwolves 115, Trail Blazers 109.
- Moneyline Pick: Timberwolves (-178)
- Total Pick: Over 221.5 (computer predicts 223.5 points)
- Pick ATS: Timberwolves (-4.5)
Recent Timberwolves vs. Trail Blazers Matchups
Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
---|---|---|---|---|---|---|
2/8/2025 | Timberwolves | -3.5 | 212.5 | -163 | +137 | 114-98 MIN |
11/13/2024 | Timberwolves | -10 | 220 | -510 | +383 | 106-98 POR |
11/12/2024 | Timberwolves | -9.5 | 221.5 | -424 | +326 | 122-108 POR |
11/8/2024 | Timberwolves | -12 | 219.5 | -735 | +513 | 127-102 MIN |
Timberwolves 2024-25 Betting Trends
- Minnesota covered the spread 39 times in 82 games last season.
- As 4.5-point favorites or more, the Timberwolves went 19-22 against the spread last season.
- Minnesota had 44 of its 82 games go over the point total last year.
- The Timberwolves put together a 40-23 record in games they were listed as the moneyline favorite last season (winning 63.5% of those games).
- Minnesota had a record of 29-14 when it played as a moneyline favorite with odds of -178 or shorter last year (67.4%).
Trail Blazers 2024-25 Betting Trends
- Portland covered 46 times in 82 games with a spread last year.
- The Trail Blazers went 29-24 as underdogs of 4.5 points or more last season.
- A total of 40 of Portland's games last year hit the over.
- The Trail Blazers won 26, or 37.7%, of the 69 games they played as underdogs last season.
- Portland had a record of 18-36, a 33.3% win rate, when it was set as the underdog by +148 or more by bookmakers last season.
Looking for NBA tickets? Head to StubHub today and see your team live.
Timberwolves vs. Trail Blazers Injury Report
Timberwolves
Timberwolves:
Leonard Miller: Out (Finger)
Trail Blazers
Trail Blazers:
Scoot Henderson: Out (Hamstring),
Damian Lillard: Out For Season (Achilles)
Timberwolves vs. Trail Blazers Game Time and TV Channel
- Game day: Wednesday, October 22, 2025
- Game time: 10 p.m. ET
- TV channel: KUNP and FDSN
- Location: Portland, Oregon
- Arena: Moda Center
- Live stream: Watch this game on Fubo (Regional restrictions may apply)
Sign up for NBA League Pass to get access to games, live and on-demand, and more for the entire season and offseason.